Vi 及化学处理的内毒素作为伤寒疫苗，对受鼠伤寒沙门氏菌-伤寒沙门氏菌杂交菌株攻击的小鼠无效。
Ineffectiveness of Vi and chemically treated endotoxins as typhoid vaccines in mice challenged with a Salmonella typhosa-Salmonella typhimurium hybrid.
作者信息
Diena B B, Ryan A, Wallace R, Ashton F E, Johnson E M, Baron L S
出版信息
Infect Immun. 1975 Dec;12(6):1470-1. doi: 10.1128/iai.12.6.1470-1471.1975.
Abstract
Purified Vi antigen, acetic anthydride-treated Salmonella typhosa endotoxin, and potassium methylate-treated S. typhosa endotoxin employed as vaccines in Swiss white mice failed to protect these animals against challenge with a virulent S. typhimurium hybrid expressing S. typhosa antigens.
摘要
在瑞士小白鼠中用作疫苗的纯化Vi抗原、经乙酸酐处理的伤寒沙门氏菌内毒素以及经甲醇钾处理的伤寒沙门氏菌内毒素，未能保护这些动物免受表达伤寒沙门氏菌抗原的有毒鼠伤寒沙门氏菌杂交菌株的攻击。
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引用本文的文献
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Evaluation of two Salmonella typhimurium hybrids as challenge organisms in a system for the assay of typhoid vaccines.评估两种鼠伤寒沙门氏菌杂交菌株作为伤寒疫苗检测系统中的攻击用生物体。
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Effectiveness of parenteral and oral typhoid vaccination in mice challenged with a Salmonella typhi-Salmonella typhimurium hybrid.经伤寒杆菌-鼠伤寒杆菌杂交菌株攻击的小鼠中，肠胃外和口服伤寒疫苗接种的有效性。
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本文引用的文献
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Chemically-modified crude endotoxins as possible typhoid vaccines.
Immunol Commun. 1973;2(1):43-56. doi: 10.3109/08820137309022880.
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Purified Vi antigens as possible typhoid vaccines.纯化Vi抗原作为可能的伤寒疫苗。
Immunol Commun. 1974;3(3):227-38. doi: 10.3109/08820137409057320.
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Infect Immun. 1974 Jun;9(6):1102-4. doi: 10.1128/iai.9.6.1102-1104.1974.
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Growth of typhoid and paratyphoid bacilli in intravenously infected mice.伤寒杆菌和副伤寒杆菌在静脉感染小鼠体内的生长情况。
Infect Immun. 1974 Oct;10(4):816-22. doi: 10.1128/iai.10.4.816-822.1974.
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Assay of typhoid vaccines with Salmonella typhosa-Salmonella typhimurium hybrids.用伤寒沙门氏菌-鼠伤寒沙门氏菌杂交菌株检测伤寒疫苗
Infect Immun. 1973 Jan;7(1):5-8. doi: 10.1128/iai.7.1.5-8.1973.
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