Iranzo A, Santamaria J, Tolosa E
Lancet. 2000 Oct 14;356(9238):1329-30. doi: 10.1016/s0140-6736(00)02824-5.
We prospectively studied the sleep patterns and laryngeal function of 20 patients with multiple system atrophy and found sleep disturbances in all subjects and vocal cord abduction dysfunction in 14 (70%). In three patients with nocturnal stridor and complete vocal cord abductor dysfunction, continuous positive airways pressure eliminated laryngeal stridor, obstructive apnoea, and haemoglobin desaturation.
我们对20例多系统萎缩患者的睡眠模式和喉部功能进行了前瞻性研究,发现所有受试者均存在睡眠障碍,14例(70%)存在声带外展功能障碍。在3例夜间喘鸣且声带外展肌完全功能障碍的患者中,持续气道正压通气消除了喉部喘鸣、阻塞性呼吸暂停和血红蛋白饱和度下降。