Chemical and Analytical Sciences Division, Oak Ridge National Laboratory, Tennessee 37831-6365, USA.
J Am Soc Mass Spectrom. 2000 Nov;11(11):951-60. doi: 10.1016/s1044-0305(00)00175-6.
Insights into the electrolysis of analytes at the electrode surface of an electrospray (ES) emitter capillary are realized through an examination of the results from off-line chronopotentiometry experiments and from mass transport calculations for flow through tubular electrodes. The expected magnitudes and trends in the interfacial potential in an ES emitter under different solution conditions and current densities, using different metal electrodes, are revealed by the chronopotentiometry data. The mass transport calculations reveal the electrode area required for complete analyte electrolysis at a given volumetric flow rate. On the basis of these two pieces of information, the design of ES emitters that may maximize and those that may minimize analyte electrolysis during ES mass spectrometry are discussed.
通过对离线计时电位法实验结果以及流经管状电极的传质计算结果进行考察，得以深入了解电喷雾（ES）发射器毛细管电极表面上分析物的电解情况。计时电位法数据揭示了在不同溶液条件和电流密度下，使用不同金属电极时，ES发射器中界面电位的预期大小和趋势。传质计算则揭示了在给定体积流速下实现分析物完全电解所需的电极面积。基于这两条信息，讨论了在ES质谱分析过程中可能使分析物电解最大化和最小化的ES发射器的设计。
