Kadnikov DV, Larock RC
Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
Org Lett. 2000 Nov 16;2(23):3643-6. doi: 10.1021/ol0065569.
A variety of substituted coumarins have been prepared in good yields by the palladium-catalyzed coupling of o-iodophenols with internal alkynes and 1 atm of carbon monoxide. Unlike most of the previous work on the palladium-catalyzed carbonylation of alkynes, the insertion of the internal alkyne occurs in preference to the insertion of CO.
通过钯催化的邻碘苯酚与内炔烃以及1个大气压一氧化碳的偶联反应，已以良好的产率制备了多种取代香豆素。与之前关于钯催化炔烃羰基化的大多数工作不同，内炔烃的插入优先于一氧化碳的插入。
