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Antimalarial amino alcohols II: anthraceneaminoethanols and anthraceneaminopropanols (1- and 9-substituted).

作者信息

Traxler J T, Moats M J, Lira E P, Huffman C W

出版信息

J Pharm Sci. 1975 Dec;64(12):1943-9. doi: 10.1002/jps.2600641207.

DOI:10.1002/jps.2600641207
PMID:1107515
Abstract

The syntheses of seven anthracene amino alcohols with one, two, or three additional substituents are described. These compounds include three 1-aminoethanols, two 9-aminoethanols, and two 9-aminopropanols, prepared from substituted anthraquinones or from 10-chloro-9-anthraldehydes. The antimalarial activity of these compounds, as well as tentative structure-activity relationships, is discussed in the light of previously published work.

摘要

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1
Antimalarial amino alcohols II: anthraceneaminoethanols and anthraceneaminopropanols (1- and 9-substituted).
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