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水牛(Bubalus bubalis)妊娠后期和泌乳早期骨代谢活动的生化指标

Biochemical indicators of bone metabolic activity in buffalo (Bubalus bubalis) during late pregnancy and early lactation.

作者信息

Ciaramella P, Piantedosi D, De Luna R, Oliva G, Consalvo F, Persechino A

机构信息

Department of Veterinary Clinical Sciences, University of Napoli Federico II, Italy.

出版信息

J Vet Med A Physiol Pathol Clin Med. 2000 Sep;47(7):431-7. doi: 10.1046/j.1439-0442.2000.00304.x.

DOI:10.1046/j.1439-0442.2000.00304.x
PMID:11076464
Abstract

Blood levels of calcium, inorganic phosphorus, magnesium, osteocalcin, intact parathyroid hormone, calcitonin, alkaline phosphatase activity, creatinine and thyroid hormones were estimated in 10 healthy buffalo during late pregnancy (30, 15 days and 7 days before calving), within 12 h after calving and 7-15-30-45 and 60 days after calving. The almost constant serum levels of calcium, phosphorus, intact parathyroid hormone, and the low calcitonin concentration indicate that these buffalo need to utilize only a little of their endogenous mineral resources. Bone-turnover could be demonstrated by variations in the serum levels of osteocalcin and alkaline phosphatase activity. A study of these bone markers could be useful for other research purposes and for future clinical application in pathological conditions.

摘要

在10头健康水牛妊娠后期(分娩前30天、15天和7天)、分娩后12小时内以及分娩后7天、15天、30天、45天和60天,对其血液中的钙、无机磷、镁、骨钙素、完整甲状旁腺激素、降钙素、碱性磷酸酶活性、肌酐和甲状腺激素水平进行了测定。钙、磷、完整甲状旁腺激素的血清水平几乎恒定,而降钙素浓度较低,这表明这些水牛仅需动用少量内源性矿物质资源。骨钙素和碱性磷酸酶活性的血清水平变化可证明骨转换情况。对这些骨标志物的研究可能有助于其他研究目的以及未来在病理状况下的临床应用。

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