Maher C O, Pollock B E
Department of Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Surg Neurol. 2000 Aug;54(2):189-93. doi: 10.1016/s0090-3019(00)00266-4.
Stereotactic radiosurgery is increasingly used for the treatment of medically unresponsive trigeminal neuralgia.
We present the case of a 69-year-old man with trigeminal neuralgia who underwent stereotactic radiosurgery after a failed balloon compression procedure. The radiosurgery also failed to provide the patient with any significant pain relief, and microvascular decompression of the trigeminal nerve was performed 10 months later. At operation, two adjacent veins and the superior cerebellar artery were noted to have focal changes consistent with atheromatous disease.
We postulate that the recent radiation exposure resulted in the observed vascular injury. As a result, patients having trigeminal neuralgia radiosurgery need to be followed carefully for possible delayed ischemic events secondary to radiation-induced vascular injury.
立体定向放射外科越来越多地用于治疗药物治疗无效的三叉神经痛。
我们报告一例69岁三叉神经痛男性患者,其在球囊压迫术失败后接受了立体定向放射外科治疗。放射外科治疗也未能为患者提供任何显著的疼痛缓解,10个月后进行了三叉神经微血管减压术。手术中,发现两条相邻静脉和小脑上动脉有与动脉粥样硬化疾病相符的局灶性改变。
我们推测近期的辐射暴露导致了观察到的血管损伤。因此,接受三叉神经痛放射外科治疗的患者需要密切随访,以预防继发于辐射诱导血管损伤的可能延迟性缺血事件。