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伽玛刀三叉神经根入区治疗原发性三叉神经痛：结果和文献复习。

Gamma Knife Radiosurgery on the Trigeminal Root Entry Zone for Idiopathic Trigeminal Neuralgia: Results and a Review of the Literature.

机构信息

Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Yonsei Med J. 2020 Feb;61(2):111-119. doi: 10.3349/ymj.2020.61.2.111.

DOI:10.3349/ymj.2020.61.2.111
PMID:31997619
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6992458/
Abstract

Trigeminal neuralgia (TN) is a chronic disorder of the trigeminal nerve characterized by repeated electrical shock-like sensations on one side of the face. It can cause severe pain in the face and disrupt or impair quality of life in patients. Options for the management of TN consist of pharmacological and surgical treatments, including Gamma Knife radiosurgery (GKRS). GKRS has been used for TN for a long time because of its low rate of complications and high success rate. Moreover, GKRS can be of use for drug-resistant TN patients who are poor surgical candidates due to medical comorbidities, patients of older age, or patients who refuse invasive therapy. We reviewed the rationale, effects, safety, and current treatment policies of GKRS for TN in view of our institution's results and a review of the literature to date.

摘要

三叉神经痛（TN）是一种慢性三叉神经疾病，表现为面部一侧反复发作电击样感觉。它可导致面部剧烈疼痛，并扰乱或损害患者的生活质量。TN 的治疗选择包括药物和手术治疗，包括伽玛刀放射外科手术（GKRS）。由于 GKRS 并发症发生率低、成功率高，因此长期以来一直用于治疗 TN。此外，对于因合并症、年龄较大或拒绝侵入性治疗等原因而不适合手术的药物难治性 TN 患者，GKRS 也有一定的应用价值。鉴于我们机构的结果和对现有文献的回顾，我们审查了 GKRS 治疗 TN 的基本原理、效果、安全性和现行治疗政策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb2b/6992458/b006e2fbc4cb/ymj-61-111-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb2b/6992458/3aa99cee78e9/ymj-61-111-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb2b/6992458/3aa99cee78e9/ymj-61-111-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb2b/6992458/0f6089af53fd/ymj-61-111-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb2b/6992458/3a196aeefb29/ymj-61-111-g003.jpg
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