Ibrahim A H, al Malki T A, Morad N
Department of Pediatric Surgery, Asir Central Hospital, College of Medicine, King Khalid University, Abha, Saudi Arabia.
J R Coll Surg Edinb. 2000 Oct;45(5):335-8.
A 21-month-old male child presented with malnutrition and painless abdominal masses. The masses were provisionally diagnosed as being abdominal lymphoma. Pre-operative investigations did not establish any other cause. The diagnosis of primary gastrointestinal aspergilloma was obtained only post-operatively by histopathology and tissue culture. Following surgery, the tumour grew rapidly and massively despite intravenous amphotericin-B, in the recommended doses. The tumour caused recurrent intestinal obstruction which necessitated multiple extensive surgical excisions. The patient finally died due to sepsis and gastrointestinal bleeding. We believe this to be the first description of a primary gastrointestinal aspergilloma with aggressive local infiltration in a non-neutropenic child.
一名21个月大的男童出现营养不良和无痛性腹部肿块。这些肿块初步诊断为腹部淋巴瘤。术前检查未发现其他病因。仅在术后通过组织病理学和组织培养才确诊为原发性胃肠道曲霉菌瘤。术后，尽管按推荐剂量静脉注射两性霉素B，肿瘤仍迅速大量生长。肿瘤导致反复肠梗阻，需要多次广泛手术切除。患者最终因败血症和胃肠道出血死亡。我们认为这是首次描述非中性粒细胞减少儿童原发性胃肠道曲霉菌瘤伴侵袭性局部浸润的病例。
