Wang X, Tian J, Yin X M, Zhang X, Wang Q Z
State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, People's Republic of China.
Appl Radiat Isot. 2000 Dec;53(6):969-74. doi: 10.1016/s0969-8043(00)00105-6.
A radioactive multitracer solution obtained from the nuclear reaction of selenium with 25 MeV/nucleon 40Ar ions was used for investigation of trace element excretion into the faeces and urine of cancerous mice. The excretion rates of 22 elements (Na, K, Rb, Mg, Ca, Sr, Ga, As, Sc, V, Cr, Mn, Co, Fe, Y, Zr, Mo, Nb, Tc, Ru, Ag and In) were simultaneously measured under strictly identical experimental conditions, in order to clarify the excretion behavior of these elements in cancerous mice. The faecal and urinary excretion rates of Mg, Sr, Ga, As, Sc, V, Cr, Mn, Co, Fe, Y, Zr, Nb, Ru and Mo in cancerous mice, showed the in highest value at 0-8 hours. The accumulative excretion of Ca, Mo, Y and Zr was decreased and Na, Fe, Mn and Co increased in tumour-bearing mice, when compared to normal mice.
一种通过硒与能量为25 MeV/核子的40Ar离子发生核反应得到的放射性多示踪剂溶液，被用于研究微量元素在患癌小鼠粪便和尿液中的排泄情况。在严格相同的实验条件下，同时测量了22种元素（钠、钾、铷、镁、钙、锶、镓、砷、钪、钒、铬、锰、钴、铁、钇、锆、钼、铌、锝、钌、银和铟）的排泄率，以阐明这些元素在患癌小鼠体内的排泄行为。患癌小鼠粪便和尿液中镁、锶、镓、砷、钪、钒、铬、锰、钴、铁、钇、锆、铌、钌和钼的排泄率在0至8小时时最高。与正常小鼠相比，荷瘤小鼠中钙、钼、钇和锆的累积排泄量减少，而钠、铁、锰和钴的排泄量增加。
