de Kanter A Y, van Geel A N, Paul M A, van Eijck C H, Henzen-Logmans S C, Kruyt R H, Krenning E P, Eggermont A M, Wiggers T
Department of Surgery, University Hospital Rotterdam/Daniel den Hoed Cancer Center, The Netherlands.
Eur J Surg Oncol. 2000 Nov;26(7):652-6. doi: 10.1053/ejso.2000.0976.
It is proposed that sentinel node biopsy should replace axillary lymph-node dissection. We analysed the role of a coordinator in the introduction of the sentinel node biopsy in breast cancer in a multi-centre setting to assure standardization and quality control.
We included 232 operable breast cancer patients. Part of the procedure was an ultrasound examination of the axilla with fine needle aspiration cytology. The sentinel node was identified with 99m-Technetium and Patent Blue.
The results of the procedure, sensitivity and false negativity, were the same for the three participating hospitals. We think this is mostly due to the coordinator who supplied information about the technique, pitfalls and results to all teams.
Our experience regarding the organization aspects of introducing the sentinel node procedure in a multi-centre setting now serves as a model in organizing its application in a much wider number of hospitals.
有人提议前哨淋巴结活检应取代腋窝淋巴结清扫术。我们分析了协调员在多中心环境下引入乳腺癌前哨淋巴结活检中的作用，以确保标准化和质量控制。
我们纳入了232例可手术乳腺癌患者。部分操作包括腋窝超声检查及细针穿刺细胞学检查。通过99m锝和专利蓝确定前哨淋巴结。
三家参与研究的医院在该操作的结果、敏感性和假阴性方面相同。我们认为这主要归功于协调员，他向所有团队提供了有关该技术、陷阱和结果的信息。
我们在多中心环境下引入前哨淋巴结手术的组织方面的经验，现在可作为在更多医院组织应用该技术的范例。
