Chien H P, Lin T P, Chen H L, Huang T W
Taiwan Provincial Chronic Disease Control Bureau, Wan-Shun-Liau, Shen-King Shiang, Taipei County, Taiwan.
Arch Pathol Lab Med. 2000 Nov;124(11):1619-22. doi: 10.5858/2000-124-1619-RMLAAW.
In a period of 18 months, we have encountered 4 cases of right middle lobe atelectasis associated with endobronchial silicotic lesions of right middle lobe bronchi. All patients had occupational exposure to mineral dusts (3 coal miners and 1 sand blaster) for months to decades.
The nature of the endobronchial silicotic lesions that caused the bronchial obstruction has been confirmed by endobronchial biopsies and energy-dispersive spectrometry of the lesions. Extrinsic compression has been excluded by careful radiographic and computed tomographic image analysis.
The endobronchial silicosis does not appear to correlate with the degree of pneumoconiosis of the lung parenchyma. The endobronchial silicosis may cause bronchial obstruction in the absence of radiographic evidence of pulmonary silicosis.
The endobronchial silicosis and consequent lung atelectasis may be associated with silica exposure.
在18个月的时间里，我们遇到了4例右中叶肺不张，伴有右中叶支气管内的硅沉着病病变。所有患者都有职业性接触矿物粉尘史（3名煤矿工人和1名喷砂工），接触时间从数月到数十年不等。
通过支气管内活检和病变的能量色散光谱分析，已证实导致支气管阻塞的支气管内硅沉着病病变的性质。通过仔细的放射学和计算机断层扫描图像分析排除了外部压迫。
支气管内硅沉着病似乎与肺实质尘肺的程度无关。支气管内硅沉着病可能在没有肺部硅沉着病放射学证据的情况下导致支气管阻塞。
支气管内硅沉着病及随之而来的肺不张可能与接触二氧化硅有关。
