Rivadeneira D E, Simmons R M, Fish S K, Gayle L, La Trenta G S, Swistel A, Osborne M P
Department of Surgery, New York Presbyterian Hospital, Cornell University Medical College, USA.
Cancer J. 2000 Sep-Oct;6(5):331-5.
The purpose of this study was to provide follow-up data regarding the incidence of local breast cancer recurrence in patients undergoing skin-sparing mastectomy versus conventional non-skin-sparing mastectomy methods.
A retrospective follow-up study and analysis were performed of patients who underwent mastectomies for invasive breast cancer at The New York Presbyterian Hospital, Cornell University Medical College and Strang-Cornell Breast Center between 1990 and 1998.
A total of 198 patients were identified in this study, and the mean follow-up was 49 months. This group included 71 patients who underwent skin-sparing mastectomy and 127 who underwent non-skin-sparing mastectomy procedures. No statistical differences in local recurrence rates were demonstrated between patients treated with skin-sparing mastectomy and those who underwent non-skin-sparing mastectomy. Local recurrence was present in four of 71 (5.6%) patients undergoing skin-sparing mastectomy and in five of 127 (3.9%) of those undergoing non-skin-sparing mastectomy.
The use of skin-sparing mastectomy does not lead to an increase in local recurrence rates when compared with conventional non-sparing mastectomies and provides for improved aesthetic results after immediate reconstruction.
本研究的目的是提供有关保乳皮肤切除术与传统非保乳皮肤切除术患者局部乳腺癌复发率的随访数据。
对1990年至1998年间在纽约长老会医院、康奈尔大学医学院和斯特朗-康奈尔乳腺中心接受浸润性乳腺癌乳房切除术的患者进行回顾性随访研究和分析。
本研究共纳入198例患者,平均随访49个月。该组包括71例行保乳皮肤切除术的患者和127例行非保乳皮肤切除术的患者。保乳皮肤切除术患者与非保乳皮肤切除术患者的局部复发率无统计学差异。71例(5.6%)行保乳皮肤切除术的患者中有4例出现局部复发,127例(3.9%)行非保乳皮肤切除术的患者中有5例出现局部复发。
与传统非保乳乳房切除术相比,保乳皮肤切除术不会导致局部复发率增加,并且在即刻重建后可改善美学效果。