Ogundele M O
Department of Immunology, Georg-August University, Göttingen, Germany.
Eur J Pediatr. 2000 Nov;159(11):793-7. doi: 10.1007/s004310000577.
Storage of human breast milk by freezing or refrigeration of milk with and without heating have been recommended. This can hardly be avoided because of the social circumstances of most mothers who are regularly separated from their infants because of work or schooling as well as the particular needs of some pre-term or sick babies to be fed with expressed breast milk. The greatest fear that has hindered the prospects of in-vitro storage of breast milk for any considerable period of time is the possibility of bacterial contamination and growth of infectious pathogens in the stored milk, thereby rendering them unsafe for human consumption. Bacteriological examination of refrigerated milks has proven their safety for human consumption for even up to 72 h. For a storage over longer periods up to 1 month, freezing at -20 degrees C could be recommended, but the most preferred method, especially for longer storage would be fresh freezing at -70 degrees C, if affordable or available. The expressed fears arising from increased titratable acidity of such stored milk samples have been unfounded, since it has been shown to be mainly attributable to levels of free fatty acids, rather than lactic acid, which might have been produced by bacterial fermentation of milk sugars.
Evidence shows that temporary storage of human milk under appropriate conditions is not dangerous for babies and infants. This would further encourage the practice of prolonged exclusive breastfeeding and allow the families to reap its multi-fold benefits.
已建议通过冷冻或冷藏母乳来储存母乳,且母乳可加热也可不加热。由于大多数母亲的社会状况,这几乎无法避免,她们因工作或上学经常与婴儿分离,以及一些早产儿或患病婴儿需要用挤出的母乳喂养的特殊需求。长期阻碍母乳体外储存前景的最大担忧是储存的母乳中可能存在细菌污染和传染性病原体生长,从而使其对人类消费不安全。对冷藏母乳的细菌学检查已证明其即使长达72小时对人类消费也是安全的。对于长达1个月的更长时间储存,建议在-20℃冷冻,但如果负担得起或有条件,最优选的方法,尤其是对于更长时间的储存,是在-70℃新鲜冷冻。对于此类储存母乳样品中可滴定酸度增加所表达的担忧是没有根据的,因为已表明这主要归因于游离脂肪酸水平,而不是可能由乳糖细菌发酵产生的乳酸。
有证据表明,在适当条件下临时储存母乳对婴儿无害。这将进一步鼓励长期纯母乳喂养的做法,并使家庭获得多重益处。