Prusiński A, Klimek A
Pol J Pharmacol Pharm. 1975 Oct;27(Suppl):189-93.
The authors present the results of own investigations about the use of both pizotifen (SandomigranR) and cyproheptadine (PeritolR). 32 sufferers were treated with pizotifen and showed positive improvement in 68% of the cases. In this group no serious side effects were found. 20 patients before administration of the drug had placebo and this helped to establish the results statistically. 25 sufferers were treated with cyproheptadine and equally positive results in 64% of the cases. In this group were noted infrequent side effects. The results of the two tests were compared with the results of other tests done with other drug. From this it has been established that the antiserotonin drugs are the most effective at present in the treatment of migraine.
作者展示了关于使用苯噻啶（桑多米granR）和赛庚啶（佩里托尔R）的自身研究结果。32名患者接受了苯噻啶治疗，68%的病例显示出积极改善。该组未发现严重副作用。20名患者在给药前服用了安慰剂，这有助于从统计学上确定结果。25名患者接受了赛庚啶治疗，64%的病例同样有积极效果。该组出现了不常见的副作用。将这两项测试的结果与使用其他药物进行的其他测试结果进行了比较。由此确定，抗血清素药物目前是治疗偏头痛最有效的药物。
