Imthurn B, Maurer-Major E
Departement Frauenheilkunde, UniversitätsSpital Zürich.
Ther Umsch. 2000 Oct;57(10):595-9. doi: 10.1024/0040-5930.57.10.595.
The most frequent symptoms of the climacteric syndrome are hot flushes. Although usually they disappear after a few years, hot flushes persist for five or more years in a quarter of the affected women. Aetiology and pathomechanism are not clear. Apart from oestrogen deficiency other diseases should be evaluated as potential causes of hot flushes such as psychosomatic disorders, hyperthyroidism and a neoplasm. The treatment of the first choice is an oestrogen replacement therapy. By assaying a single serum sample for oestradiol an oestrogen replacement therapy can be monitored reliably only in the case of transdermal application.
更年期综合征最常见的症状是潮热。虽然潮热通常在几年后消失，但四分之一的受影响女性会持续出现五年或更长时间。病因和发病机制尚不清楚。除雌激素缺乏外，其他疾病也应作为潮热的潜在原因进行评估，如心身疾病、甲状腺功能亢进和肿瘤。首选治疗方法是雌激素替代疗法。仅在经皮应用的情况下，通过检测单次血清样本中的雌二醇，才能可靠地监测雌激素替代疗法。
