[Transdermal estrogen spray in therapy of postmenopausal syndrome].

OBJECTIVE

To show possibilities of new application method of estrogen replacement therapy - mettered-dose transdermal spray.

DESIGN

Review articleResults: Transdermal spray contains 1.53 mg estradiol in one dose. It gives possibility of individual aproach in estradiol application 1, 2 or 3 doses daily. About 85% of patients showed the significant reduction of hot flushes. Perfect safety profile is predicted especially in cardiovascular point.