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Synthesis of slagenins A, B, and C.

作者信息

Barrios Sosa A C, Yakushijin K, Horne D A

机构信息

Department of Chemistry, Oregon State University, Corvallis, Oregon 97331, USA.

出版信息

Org Lett. 2000 Nov 2;2(22):3443-4. doi: 10.1021/ol000233v.

Abstract

[structure: see text] A short synthesis of the marine sponge metabolites slagenins A (1), B (2), and C (3) is described. The synthetic route features the preparation of beta-hydroxyimidazolone 4 from ornithine and its subsequent oxidative cyclization to the slagenin core.

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