Barrios Sosa A C, Yakushijin K, Horne D A
Department of Chemistry, Oregon State University, Corvallis, Oregon 97331, USA.
Org Lett. 2000 Nov 2;2(22):3443-4. doi: 10.1021/ol000233v.
[structure: see text] A short synthesis of the marine sponge metabolites slagenins A (1), B (2), and C (3) is described. The synthetic route features the preparation of beta-hydroxyimidazolone 4 from ornithine and its subsequent oxidative cyclization to the slagenin core.
