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[外阴阴道念珠菌病中酵母菌菌种鉴定:对制霉菌素的敏感性]

[Yeast species identification in vulvovaginal candidiasis: susceptibility to nystatin].

作者信息

Lisiak M, Kłyszejko C, Marcinkowski Z, Gwieździński Z

机构信息

Oddziału Połoznictwa i Patologii Ciazy Szpitala Miejskiego im dr. E. Warmińskiego w Bydgoszczy.

出版信息

Ginekol Pol. 2000 Sep;71(9):959-63.


DOI:
PMID:11082956
Abstract

OBJECTIVE: The rates of Candida species and susceptibility to nystatin were evaluated. MATERIALS AND METHODS: In the period from January 1, 1998 to December 31, 1998 mycological tests have been carried out for identification of yeast species in the group of pregnant and delivering women hospitalized in the Obstetrics-Gynecological Departments of the Municipal Hospital in Bydgoszcz. We used two commercial media: Albicans ID and CHROMagar Candida. Noted have been 389 positive inoculation results for Candida from vaginal secretions. RESULTS AND CONCLUSIONS: From the total number of 416 differentiated fungus strains decidedly dominant was the species Candida albicans--constituting 81.97% of all strains. The second frequently occurring fungus species was Candida glabrata--11.06%. Further species were C. krusei--2.16%, C. tropicalis--1.20% and C. guilliermondii--1.20%. In 10 cases (2.41%)--in spite of carrying out the laboratory activities that are necessary in such a situation--the species type of tested strains could not be determined. The simultaneous occurrence of two Candida species has been noted in material originating from 27 women (6.94% of cases). Defining the drug-resistance of 93 Candida species strains against nystatin by means of the disk-diffusion method--it has been started that this drug is highly effective--81.72% of sensitive strains.

摘要

目的:评估念珠菌属的发生率及对制霉菌素的敏感性。 材料与方法:在1998年1月1日至1998年12月31日期间,对比得哥什市立医院妇产科住院的孕妇和产妇进行了真菌学检测,以鉴定酵母菌种类。我们使用了两种商业培养基:白色念珠菌鉴定培养基和CHROMagar念珠菌培养基。记录了389例阴道分泌物念珠菌阳性接种结果。 结果与结论:在总共416株已鉴定的真菌菌株中,白色念珠菌明显占主导地位,占所有菌株的81.97%。第二常见的真菌种类是光滑念珠菌,占11.06%。其他种类包括克柔念珠菌(2.16%)、热带念珠菌(1.20%)和季也蒙念珠菌(1.20%)。在10例(2.41%)病例中,尽管进行了这种情况下必要的实验室检测,但仍无法确定受试菌株种类。在来自27名女性的样本中(占病例的6.94%)发现了两种念珠菌同时存在的情况。通过纸片扩散法确定了93株念珠菌菌株对制霉菌素的耐药性,结果表明该药物非常有效,敏感菌株占81.72%。

相似文献

[1]
[Yeast species identification in vulvovaginal candidiasis: susceptibility to nystatin].

Ginekol Pol. 2000-9

[2]
[INVESTIGATION ON ANTIFUNGAL SUSCEPTIBILITY OF CANDIDA YEASTS IN PREGNANT PATIENTS WITH CONFIRMED VULVOVAGINAL CANDIDIASIS AND THEIR NEWBORNS.].

Akush Ginekol (Sofiia). 2016

[3]
In vitro susceptibility profile of 200 recent clinical isolates of Candida spp. to topical antifungal treatments of vulvovaginal candidiasis, the imidazoles and nystatin agents.

J Mycol Med. 2014-12

[4]
Guideline: vulvovaginal candidosis (AWMF 015/072), S2k (excluding chronic mucocutaneous candidosis).

Mycoses. 2015-3

[5]
Guideline vulvovaginal candidosis (2010) of the German Society for Gynecology and Obstetrics, the Working Group for Infections and Infectimmunology in Gynecology and Obstetrics, the German Society of Dermatology, the Board of German Dermatologists and the German Speaking Mycological Society.

Mycoses. 2012-7

[6]
In vitro fluconazole and nystatin susceptibility and clinical outcome in complicated vulvovaginal candidosis.

Mycoses. 2010-4-6

[7]
In vitro antifungal sensitivity of fluconazole, clotrimazole and nystatin against vaginal candidiasis in females of childbearing age.

J Ayub Med Coll Abbottabad. 2010

[8]
[In vitro assessment of the sensitivity of Candida albicans strains isolated from the vagina on basis antimycotics].

Ginekol Pol. 2000-9

[9]
[Vaginal candidiasis: etiology and sensitivity profile to antifungal agents in clinical use].

Rev Argent Microbiol. 2001

[10]
Antifungal activity of propolis extract against yeasts isolated from vaginal exudates.

J Altern Complement Med. 2010-3

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