Kümpfel T, Lechner C, Auer D, Kraft E, Lydtin H, Trenkwalder C
Max Planck Institut of Psychiatry, Munich, Germany.
Acta Neurol Scand. 2000 Nov;102(5):337-9. doi: 10.1034/j.1600-0404.2000.102005337.x.
We describe a 77-year-old woman who developed a confusional state, cognitive impairment, behavioural abnormalities and dysphasia after treatment of hypercalcaemia. Repeated EEG recording revealed rhythmic sharp-wave activity over the right parietal-occipital lobe. Magnetic resonance imaging (MRI) showed marked hyperintense signal changes bilaterally. The diagnosis of a non-convulsive status epilepticus (NCSE) was made. With antiepileptic treatment the patient improved and MRI as well as EEG changes were almost all reversible. NCSE is an important differential diagnosis of patients with neuropsychiatric symptoms and can develop after rapid lowering of serum calcium levels in hypercalcaemia.
我们描述了一位77岁女性，她在高钙血症治疗后出现了意识模糊状态、认知障碍、行为异常和言语困难。多次脑电图记录显示右侧顶枕叶有节律性锐波活动。磁共振成像（MRI）显示双侧有明显的高信号改变。诊断为非惊厥性癫痫持续状态（NCSE）。经过抗癫痫治疗，患者病情好转，MRI及脑电图改变几乎全部可逆。NCSE是神经精神症状患者的重要鉴别诊断，可在高钙血症患者血清钙水平快速降低后发生。
