Unidad de Reumatología Pediátrica, Hospital La Paz, Madrid.
An Esp Pediatr. 2000 Oct;53(4):314-7.
To evaluate the therapeutic response to intraarticular triamcinolone acetonide injections in patients with juvenile idiopathic arthritis.
Eight-eight patients were prospectively evaluated after receiving one or more intraarticular triamcinolone acetonide injections. A total of 194 joints were injected: 68 joints in 39 children with oligoarticular onset juvenile idiopathic arthritis, 36 joints in 17 children with polyarticular onset, 67 joints in 20 children with systemic onset, and 23 joints in 12 children with spondyloarthropathy.
Full resolution of signs of inflammation was achieved in 131 of 194 joints (67.5%). The percentage of remission was significantly lower in patients with systemic onset of the disease (36% versus 80% in the other groups). At the 6-month follow-up, 70% of the joints remained in remission. No significant complications were observed.
Intraarticular triamcinolone injections are safe and effective in children with chronic arthritis.
评估关节内注射曲安奈德对幼年特发性关节炎患者的治疗反应。
对88例接受一次或多次关节内注射曲安奈德的患者进行前瞻性评估。共注射了194个关节：39例少关节型幼年特发性关节炎患儿的68个关节、17例多关节型患儿的36个关节、20例全身型患儿的67个关节以及12例脊柱关节病患儿的23个关节。
194个关节中的131个（67.5%）炎症体征完全消退。疾病全身型患者的缓解率显著低于其他组（36% 对比其他组的80%）。在6个月的随访中，70%的关节仍处于缓解状态。未观察到明显并发症。
关节内注射曲安奈德对慢性关节炎患儿安全有效。
