使用非接触式激光组织血流仪评估肠道活力。
Assessment of intestinal viability using a non-contact laser tissue blood flowmeter.
作者信息
Ando M, Ito M, Nihei Z, Sugihara K
机构信息
Department of Digestive Surgery, Tokyo Medical and Dental University, Graduate School, Tokyo, Japan.
出版信息
Am J Surg. 2000 Sep;180(3):176-80. doi: 10.1016/s0002-9610(00)00444-x.
BACKGROUND
Intraoperative assessment of small intestinal viability following ischemic insult from arterial occlusion has remained difficult. The purpose of the present study was to assess the applicability of non-contact tissue blood flowmeter (NCLBF) with regard to intraoperative assessment of intestinal viability.
METHODS
Using the ischemia-reperfusion model of rabbits, the relationship between the records of NCLBF, pulse oximetry (PO), and histological grade and the comparison of accuracy of intestinal viability among NCLBF, PO, and fluorescein (FL) were examined.
RESULTS
There was a significant relationship between NCLBF and the histological grade (coefficient-0.80, P <0.0001); however, PO was not related. The accuracy and sensitivity of bowel viability of NCLBF (76%, 88%) were better than those of PO (58%, 23%) and FL (48%, 4%), respectively (P <0.001).
CONCLUSIONS
NCLBF is useful to assess intestinal viability, suggesting the possibility of clinical use.
背景
因动脉闭塞导致缺血性损伤后，术中评估小肠活力一直颇具难度。本研究旨在评估非接触式组织血流仪（NCLBF）在术中评估肠道活力方面的适用性。
方法
采用兔缺血再灌注模型，研究NCLBF记录、脉搏血氧饱和度（PO）与组织学分级之间的关系，并比较NCLBF、PO和荧光素（FL）在评估肠道活力准确性方面的差异。
结果
NCLBF与组织学分级之间存在显著相关性（系数为-0.80，P<0.0001）；然而，PO与之无关。NCLBF评估肠活力的准确性和敏感性分别为76%和88%，优于PO（58%，23%）和FL（48%，4%）（P<0.001）。
结论
NCLBF有助于评估肠道活力，提示其具有临床应用的可能性。
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