准分子原位角膜磨镶术相关的视神经病变
Optic neuropathy associated with laser in situ keratomileusis.
作者信息
Lee A G, Kohnen T, Ebner R, Bennett J L, Miller N R, Carlow T J, Koch D D
机构信息
Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
出版信息
J Cataract Refract Surg. 2000 Nov;26(11):1581-4. doi: 10.1016/s0886-3350(00)00688-x.
PURPOSE
To report 4 cases of optic neuropathy following laser in situ keratomileusis (LASIK).
SETTING
Tertiary Care ophthalmic practices.
METHODS
In this retrospective observational case series, 4 patients who developed acute visual loss following LASIK are reported. All had clinical evidence of optic neuropathy. Two had optic disc edema and 2 had normal appearing optic discs initially. None of the patients experienced significant visual recovery, and all developed optic atrophy in the affected eye.
RESULTS
All patients had evaluations for alternative etiologies of their optic neuropathy, with negative results. All patients were therefore presumed to have experienced an ischemic optic neuropathy following LASIK.
CONCLUSIONS
Patients who have LASIK may experience an acute anterior or retrobulbar optic neuropathy. The etiology is unknown but may be related to the marked increase in intraocular pressure that occurs during a portion of the procedure.
目的
报告4例准分子原位角膜磨镶术（LASIK）后发生的视神经病变。
机构
三级眼科医疗实践机构。
方法
在这个回顾性观察病例系列中，报告了4例LASIK术后出现急性视力丧失的患者。所有患者均有视神经病变的临床证据。2例有视盘水肿，2例最初视盘外观正常。所有患者均未出现明显的视力恢复，患眼均发生视神经萎缩。
结果
所有患者均对其视神经病变的其他病因进行了评估，结果均为阴性。因此，所有患者均被推测在LASIK术后发生了缺血性视神经病变。
结论
接受LASIK手术的患者可能会发生急性前部或球后视神经病变。病因不明，但可能与手术过程中部分时段出现的眼压显著升高有关。
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