He Fanglin, Yang Jie, Jia Renbing, Zhang Jing
Department of Ophthalmology, Shanghai Key Laboratory of Orbital Disease and Ocular Oncology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.
Exp Ther Med. 2019 Oct;18(4):2599-2607. doi: 10.3892/etm.2019.7831. Epub 2019 Jul 30.
The aim of the present study was to investigate the potential changes in the choroidal thickness (CT) after surgical implantation of collamer lens (ICL) and to determine whether the variations in CT were associated with the degree of myopia. In the study, 98 eyes from 98 myopia patients were divided into two groups according to the degree of myopia: High myopia and super-high myopia. All eyes were measured using the swept-source optical coherence tomography (SS-OCT) technique. CT and CT variations were also recorded. The foveal CT increased significantly in high-myopia patients at 2 h after surgery and 3 months after surgery; the same tendency was observed in the inner nasal CT and outer nasal CT at the same time-points. In patients with super-high myopia, the subfoveal CT increased significantly at 2 h and 3 months after surgery compared with the pre-operative values. No statistically significant differences were obtained in any of the nine different choroidal regions evaluated at post-operative week 1 and post-operative month one. Furthermore, the increase in the subfoveal CT in the super-myopia group was significantly higher than that in the high-myopia group at 2 h and at 3 months after ICL. The results of the present study indicated that the CT significantly increased 2 h after the surgery and then reached a peak at 3 months, particularly in the subfoveal and nasal areas. A higher degree of myopia was associated with greater subfoveal choroidal changes.
本研究的目的是调查植入可折叠人工晶体（ICL）手术后脉络膜厚度（CT）的潜在变化，并确定CT的变化是否与近视程度相关。在该研究中，98例近视患者的98只眼根据近视程度分为两组：高度近视和超高度近视。所有眼睛均使用扫频光学相干断层扫描（SS-OCT）技术进行测量。同时记录CT及CT变化情况。高度近视患者术后2小时及术后3个月时，黄斑中心凹CT显著增加；在同一时间点，鼻内侧CT和鼻外侧CT也观察到相同趋势。超高度近视患者术后2小时及3个月时，黄斑中心凹下CT较术前显著增加。术后1周及术后1个月时，在评估的9个不同脉络膜区域中，均未获得统计学上的显著差异。此外，ICL术后2小时及3个月时，超高度近视组黄斑中心凹下CT的增加显著高于高度近视组。本研究结果表明，术后2小时CT显著增加，然后在3个月时达到峰值，尤其是在黄斑中心凹下和鼻侧区域。近视程度越高，黄斑中心凹下脉络膜变化越大。
