Li R
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.
Curr Biol. 2000 Nov 2;10(21):R781-4. doi: 10.1016/s0960-9822(00)00762-4.
Yeast cells must segregate sister chromosomes to the opposite sides of the bud neck during mitosis. A pathway has been identified, involving a small GTPase, which prevents the onset of cytokinesis until one of the spindle poles has migrated into the bud.
酵母细胞在有丝分裂期间必须将姐妹染色单体分离到芽颈的两侧。现已确定了一条涉及小GTP酶的途径,该途径可防止胞质分裂的开始,直到其中一个纺锤极迁移到芽中。