Bernard P M
Département de Médecine sociale et préventive, Pavillon de l'Est, 2180, chemin Sainte-Foy, Université Laval, Québec, Canada G1K 7P4.
Rev Epidemiol Sante Publique. 2000 Oct;48(5):484-9.
This paper proposes an approach for calculating the normal confidence interval of a weighted summary measure which requires a particular continuous transformation for its variance estimation. By using the transformation properties and applying the delta method, the variance of transformed measure is easily expressed in terms of the transformed specific measure variances and the squared weights. The confidence limits of the summary measure are easily deduced by inverse transformation of those of transformed measure. The method is illustrated by applying it to some well known epidemiological measures. It seems appropriate for application in stratified analysis context where size allows normal approximation.
本文提出了一种计算加权汇总指标正态置信区间的方法,该方法在估计方差时需要进行特定的连续变换。通过利用变换性质并应用德尔塔法,变换后指标的方差可以很容易地用变换后的特定指标方差和权重的平方表示出来。汇总指标的置信限可通过对变换后指标的置信限进行逆变换轻松推导得出。通过将该方法应用于一些著名的流行病学指标对其进行了说明。该方法似乎适用于样本量允许正态近似的分层分析情况。