Chernata L I, Vershigora A E
Zh Mikrobiol Epidemiol Immunobiol. 1975 May(5):123-7.
For the purpose of ascertaining the peculiarities of cellular differentiation of lymphoid cells of the palatine tonsils experiments were conducted on rabbits immunized intravenously and subcutaneously with streptococcus and paratyphoid B antigens; a study was made (in the blast-transformation reaction) of a comparative response of the lymphocytes of the palatine tonsils, the thymus, the spleen, the appendix and the regional lymph node. In case of stimulation with the specific microbial antigens and PHA the proliferative response was greater in the culture of the splenic lymphocytes and the regional lymph node than in the culture of the lymphocytes of the palatine tonsils and the appendix. The thymus lymphocytes responded to PHA only. A conclusion was drawn that the paratyphoid B and streptococcus antigens penetrating into the lymphoid tissue by hematogenic route stimulated a relatively low percentage of lymphocytes of the palatine tonsils and the appendix in comparison with the regional lymph node and the spleen.
为了确定腭扁桃体淋巴样细胞的细胞分化特点，对静脉内和皮下注射链球菌及副伤寒B抗原免疫的家兔进行了实验；对腭扁桃体、胸腺、脾脏、阑尾及局部淋巴结的淋巴细胞的比较反应（在母细胞转化反应中）进行了研究。在用特异性微生物抗原和PHA刺激时，脾淋巴细胞和局部淋巴结培养物中的增殖反应比腭扁桃体和阑尾淋巴细胞培养物中的更大。胸腺淋巴细胞仅对PHA有反应。得出的结论是，经血液途径渗入淋巴组织的副伤寒B和链球菌抗原，与局部淋巴结和脾脏相比，刺激腭扁桃体和阑尾淋巴细胞的比例相对较低。
