Shchipkova N I, Pekhov A P, Schchipkov V P
Zh Mikrobiol Epidemiol Immunobiol. 1975 May(5):33-6.
A study was made of the genetic determinants of the O-antigenicity in the E. coli, O25 and O86 serological groups in experiments on conjugation and transduction. In analysis of genetic recombinants selected from the crosses of the serologically typed and nontyped bacteria there was revealed a relationship between the inheritance of the antigenic signs (O25+ and O86+) and the capacity of histidine to synthesis. The S-form and the O25-antigenicity signs were readily cotransduced with the his+ marker, this pointing to the close linking of the corresponding genes loci on the bacterial chromosome.
在接合和转导实验中,对大肠杆菌O25和O86血清型组中O抗原性的遗传决定因素进行了研究。在对从血清分型和未分型细菌杂交中选出的遗传重组体的分析中,发现了抗原标志(O25 +和O86 +)的遗传与组氨酸合成能力之间的关系。S型和O25抗原性标志很容易与his +标记共转导,这表明细菌染色体上相应基因座紧密连锁。