Ravenscroft J, Goodfield M J, Evans E G
Department of Dermatology, Leeds General Infirmary, West Yorkshire, England.
Pediatr Dermatol. 2000 Sep-Oct;17(5):407-9. doi: 10.1046/j.1525-1470.2000.017005407.x.
We report a Caucasian family of two veterinary practitioners and their two children, ages 2 years and 6 months, simultaneously infected with the dermatophyte Trichophyton tonsurans, causing tinea capitis and tinea corporis in the children and tinea corporis in the parents. The parents and older child were successfully treated with oral terbinafine. The infant clinically responded to treatment with topical terbinafine and ketoconazole shampoo but presented with recurrent tinea capitis 12 months later, from which T. tonsurans was cultured. At this time, scalpbrush samples from the other family members failed to culture any fungi, and neither were fungi isolated from the family hairbrushes. The infant then received oral terbinafine, resulting in clinical and mycologic cure. After a further 12 months follow-up, there has been no mycologic evidence of recurrence in any family member.
我们报告了一个白人家庭，父母是两名兽医，他们有两个孩子，分别为2岁和6个月大，同时感染了皮肤癣菌断发毛癣菌，导致孩子患头癣和体癣，父母患体癣。父母和较大的孩子口服特比萘芬治疗成功。婴儿外用特比萘芬和酮康唑洗发水治疗后临床症状有改善，但12个月后出现头癣复发，培养出断发毛癣菌。此时，其他家庭成员的头皮刷样本未培养出任何真菌，家庭用发刷中也未分离出真菌。婴儿随后接受口服特比萘芬治疗，实现了临床和真菌学治愈。经过进一步12个月的随访，没有任何家庭成员有真菌学复发的证据。
