Lindqvist B, Wahlin A
Acta Med Scand. 1975 Dec;198(6):505-9. doi: 10.1111/j.0954-6820.1975.tb19582.x.
A total of 291 urine sediments from 255 patients with various renal or urinary tract diseases have been studied by phase contrast microscopy. Based upon morphological criteria, leucocytes were distinguished from renal epithelial cells and the white blood cells were classified either as mononuclear or polynuclear in 179 patients. The percentage of the different cell types varied considerably between and within the different diseases. The median values for polynuclear granulocytes were higher than 90% in bacterial renal or urinary tract disease and in polycystic kidney disease. In interstitial nephritis, nephrosclerosis and in renal transplanted patients the percentage of polynuclear granulocytes was somewhat lower, 76-85%. In diabetes, amyloidosis, tubular nephrosis (necrosis) glomerulonephritis, lupus nephritis and endemic benign nephropathy there were 14-66% polynuclear granulocytes. 29-33% mononuclear leucocytes were found in lupus nephritis and endemic benign nephropathy. The greatest proportion of renal epithelial cells was found in endemic benign nephropathy, namely 49%. 36% renal epithelial cells were found in tubular nephrosis (necrosis) and in glomerulonephritis. The technique is rapid and inexpensive. It facilitates differential diagnostics of urinary tract disease with pyuria.
我们采用相差显微镜对255例患有各种肾脏或泌尿系统疾病患者的291份尿沉渣进行了研究。根据形态学标准，在179例患者中区分了白细胞与肾上皮细胞，并将白细胞分类为单核或多核。不同细胞类型的百分比在不同疾病之间以及同一疾病内部差异很大。在细菌性肾脏或泌尿系统疾病以及多囊肾疾病中，多核粒细胞的中位数高于90%。在间质性肾炎、肾硬化症以及肾移植患者中，多核粒细胞的百分比略低，为76 - 85%。在糖尿病、淀粉样变性、肾小管肾病（坏死）、肾小球肾炎、狼疮性肾炎和地方性良性肾病中，多核粒细胞占14 - 66%。在狼疮性肾炎和地方性良性肾病中发现单核白细胞占29 - 33%。肾上皮细胞比例最高的是地方性良性肾病，为49%。在肾小管肾病（坏死）和肾小球肾炎中发现肾上皮细胞占36%。该技术快速且成本低廉。它有助于对伴有脓尿的泌尿系统疾病进行鉴别诊断。
