Yu S C, Ng B T, Chan W K, Chua L P
Nanyang Technological University, Thermal and Fluids Engineering Division, School of Mechanical and Production Engineering, 639798, Singapore.
Med Eng Phys. 2000 Jul;22(6):381-93. doi: 10.1016/s1350-4533(00)00045-x.
The effects of impeller geometry on the performance of a centrifugal blood pump model [the MSCBP design of Akamatsu and Tsukiya (The Seventh Asian Congress of Fluid Mechanics (1997), 7-10) at a 1:1 scale] have been investigated both experimentally and computationally. Four impeller designs were tested for pump hydraulic performance at the operating point (i.e. 2000 rpm), using blood analog as the working fluid. Each impeller has seven blades with different configurations including the radial straight blade and backward swept blade designs. The results show that both designs can achieve a stable head of about 100 mm Hg at the operating point. Subsequent investigations involved the visualization of the relative flow field within the impeller passages via the image de-rotation system coupled with a 2.5 W argon ion laser. Flow structures in all sectors of each impeller were examined and discussed. To further quantify the possible effects of blade geometry to thrombus formation and hemolysis, computational fluid dynamics (CFD) was used to simulate a simplified two-dimensional blade-to-blade flow analysis so as to estimate the shear stress levels. The results indicate that the stress levels found within the blade passages are generally below the threshold level of 150 N/m(2) for extensive erythrocyte damage to occur. There are some localized regions near the leading edge of the blades where the stress levels are 60% above the threshold level. However, given such a short residence time for the fluid particles to go through these high shear stress regions, their effects appear to be insignificant.
研究了叶轮几何形状对离心式血泵模型[赤松和月谷的MSCBP设计(第七届亚洲流体力学大会(1997年),第7 - 10页),1:1比例]性能的影响,进行了实验和计算研究。以血液模拟物作为工作流体,在运行点(即2000转/分钟)对四种叶轮设计进行了泵水力性能测试。每个叶轮有七个叶片,具有不同的构型,包括径向直叶片和后掠叶片设计。结果表明,两种设计在运行点都能实现约100毫米汞柱的稳定扬程。随后的研究涉及通过与2.5瓦氩离子激光器耦合的图像去旋转系统对叶轮通道内的相对流场进行可视化。对每个叶轮所有扇区的流动结构进行了检查和讨论。为了进一步量化叶片几何形状对血栓形成和溶血的可能影响,使用计算流体动力学(CFD)模拟简化的二维叶间流动分析,以估计剪切应力水平。结果表明,叶片通道内的应力水平通常低于150 N/m²的阈值水平,不会发生广泛的红细胞损伤。在叶片前缘附近有一些局部区域,应力水平比阈值水平高60%。然而,鉴于流体颗粒通过这些高剪切应力区域的停留时间很短,它们的影响似乎微不足道。