Localization of antisera to LHbeta and FSHbeta in the rat pituitary gland.

Pituitary glands from adult male and female rats were stained by the immunocytochemical bridge technique with antisera to ovine LHbeta and human FSHbeta. Peroxidase reaction product was localized in the same PAS-positive cells with both antisera. The cells varied in size and topographical distribution within the pars distalis. These observations support the concept that a single cell type is responsible for the synthesis of both LH and FSH in the rat.