一种用于苏氨酸位点连接的程序：在糖肽可控全合成中的应用。
A program for ligation at threonine sites: application to the controlled total synthesis of glycopeptides.
作者信息
Chen Jin, Wang Ping, Zhu Jianglong, Wan Qian, Danishefsky Samuel J
机构信息
Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10065, USA.
出版信息
Tetrahedron. 2010 Mar 27;66(13):2277-2283. doi: 10.1016/j.tet.2010.01.067.
Abstract
A method by which to accomplish formal threonine ligation has been developed. The method accomplishes ligations of two peptide domains. We have also demonstrated the ability to successfully ligate two independent glycopeptide domains.
摘要
一种实现苏氨酸正式连接的方法已经被开发出来。该方法实现了两个肽结构域的连接。我们还证明了成功连接两个独立糖肽结构域的能力。
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