Suppr超能文献

自杀倾向青少年中的焦虑症

Anxiety disorders in suicidal youth.

作者信息

Strauss J, Birmaher B, Bridge J, Axelson D, Chiappetta L, Brent D, Ryan N

机构信息

Division of Child Psychiatry, University of Pittsburgh Medical Center, Pennsylvania, USA.

出版信息

Can J Psychiatry. 2000 Oct;45(8):739-45. doi: 10.1177/070674370004500807.

Abstract

OBJECTIVE

To test the hypothesis that anxiety disorders are associated with suicidal ideation and suicide attempts in a child and adolescent sample referred to a clinic.

METHOD

The sample comprised 1979 patients aged 5 to 19 years who were assessed using the Schedule for Affective Disorders and Schizophrenia for School Aged Children--Present Episode (K-SADS-P) at an outpatient mood and anxiety disorders clinic. Subjects were stratified by age and categorized into mutually exclusive groups as being nonsuicidal (n = 817), having suicidal ideation (n = 768), or having attempted suicide (n = 394) in the current episode. Psychiatric diagnoses based on DSM-IV criteria were compared to determine if anxiety disorders were a risk factor for suicidal ideation and suicide attempts. Logistic regression was used to control for significant demographic characteristics and comorbid disorders.

RESULTS

After stratifying by age, we found no differences across the 3 groups (ideators, attempters, and nonsuicidal youth) in rates of an anxiety disorder in general or in specific rates of panic disorder, agoraphobia, social phobia, simple phobia, and obsessive-compulsive disorder. Two salient findings involving anxiety disorders were noted with regression analysis. In younger children (age < or = 15 years), attempters had a significantly lower prevalence of separation anxiety disorder (SAD), compared with ideators (OR = 0.30; 95%CI, 0.11 to 0.80; P = 0.006) and nonsuicidal youngsters (OR = 0.14; 95%CI, 0.05 to 0.39; P < 0.0001). In older children (age > 15 years), generalized anxiety disorder (GAD) was more prevalent in ideators (OR = 1.65; 95%CI, 1.03 to 2.66; P = 0.03) than in nonsuicidal patients.

CONCLUSIONS

Based on this clinical sample, the relation between pediatric anxiety disorder and suicidal ideation and suicide attempts is not straightforward. However, further studies in nonreferred samples are warranted.

摘要

目的

检验这样一种假设,即在一家诊所就诊的儿童和青少年样本中,焦虑症与自杀观念及自杀未遂有关。

方法

样本包括1979名年龄在5至19岁的患者,他们在一家门诊情绪与焦虑症诊所接受了儿童情感障碍和精神分裂症评定量表——当前发作版(K-SADS-P)的评估。受试者按年龄分层,并分为相互排斥的几组,即当前发作中无自杀行为(n = 817)、有自杀观念(n = 768)或有自杀未遂行为(n = 394)。比较基于《精神疾病诊断与统计手册》第四版(DSM-IV)标准的精神科诊断,以确定焦虑症是否是自杀观念和自杀未遂的危险因素。采用逻辑回归来控制显著的人口统计学特征和共病。

结果

按年龄分层后,我们发现三组(有自杀观念者、有自杀未遂行为者和无自杀行为的青少年)在一般焦虑症发生率或惊恐障碍、广场恐惧症、社交恐惧症、单纯恐惧症和强迫症的特定发生率方面没有差异。回归分析发现了两个与焦虑症有关的显著结果。在年幼儿童(年龄≤15岁)中,有自杀未遂行为者的分离焦虑症(SAD)患病率显著低于有自杀观念者(比值比[OR]=0.30;95%置信区间[CI],0.11至0.80;P = 0.006)和无自杀行为的青少年(OR = 0.14;95%CI,0.05至0.39;P < 0.0001)。在年长儿童(年龄>15岁)中,有自杀观念者的广泛性焦虑症(GAD)患病率高于无自杀行为的患者(OR = 1.65;95%CI,1.03至2.66;P = 0.03)。

结论

基于这个临床样本,儿童焦虑症与自杀观念及自杀未遂之间的关系并不简单。然而,有必要在未转诊样本中进行进一步研究。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验