Morse J L, Jones N L, Anderson G D
Am Rev Respir Dis. 1976 Jan;113(1):89-92. doi: 10.1164/arrd.1976.113.1.89.
A double blind study of 5 asthmatic subjects in remission demonstrated that the severity of bronchoconstriction after exercise was decreased by a single oral dose of 5 mg of terbutaline. The effect lasted for at least 6 hours and was significantly better than the protection afforded by 20 mg of metaproterenol, which was itself more effective than a placebo. In these doses, neither terbutaline nor metaproterenol affected heart rate or blood pressure at rest or in exercise, and no drug-induced side effects were found.
一项针对5名缓解期哮喘患者的双盲研究表明，单次口服5毫克特布他林可减轻运动后支气管收缩的严重程度。这种效果持续至少6小时，且明显优于20毫克间羟异丙肾上腺素提供的保护作用，而间羟异丙肾上腺素本身就比安慰剂更有效。在这些剂量下，特布他林和间羟异丙肾上腺素在静息或运动时均不影响心率或血压，且未发现药物引起的副作用。
