干扰素诱导剂在人类单纯疱疹性角膜炎中的治疗应用。
Therapeutic use of inducers of interferon on Herpes simplex keratitis in humans.
作者信息
Galin M A, Chowchuvech E, Kronenberg B
出版信息
Ann Ophthalmol. 1976 Jan;8(1):72-6.
PMID:1108735
Abstract
The double-stranded RNA interferon inducer polyinosinic-polycytidylic acid (In-Cn) was used to treat acute dendritic keratitis in man in a double-blind manner with IDU. The success rate for this agent was similar to IDU and was found efficacious in cases not responsive to IDU. Prophylaxis with In-Cn did not prevent recurrences of epithelial herpes, but such recurrences were responsive to IDU or In-Cn.
摘要
双链RNA干扰素诱导剂聚肌苷酸-聚胞苷酸（In-Cn）与碘苷（IDU）以双盲方式用于治疗人类急性树枝状角膜炎。该药物的成功率与碘苷相似，且在对碘苷无反应的病例中被发现有效。用In-Cn进行预防并不能防止上皮性疱疹复发，但此类复发对碘苷或In-Cn有反应。
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