Fellner M J, Katz J M
Arch Dermatol. 1976 Jan;112(1):75-7.
A 78-year-old woman with Parkinson disease developed tense bullous lesions on the chest, arms, and in the groin that were diagnosed as bullous pemphigoid. Histologic examination, as well as immunofluorescence tests, confirmed this diagnosis. The possibility of a drug-induced disease was considered because she was taking seven different medications. Furosemide (Lasix) was suspected primarily. Complete clearing occurred with prednisone therapy, but readministration of furosemide resulted in bulla formation.
一名78岁的帕金森病女性患者胸部、手臂和腹股沟出现紧张性大疱性皮损，诊断为大疱性类天疱疮。组织学检查及免疫荧光试验均证实了这一诊断。由于她正在服用七种不同药物，因此考虑了药物性疾病的可能性。主要怀疑是速尿（速尿灵）。泼尼松治疗后皮损完全消退，但再次服用速尿导致水疱形成。
