Haag M, Selbach J, Keberle E
Medizinische Klinik, Caritas-Krankenhauses Bad Mergentheim.
Med Klin (Munich). 2000 Oct 15;95(10):592-6. doi: 10.1007/pl00002068.
A 20-year-old asymptomatic man was admitted with severe hypertension (250/150 mm Hg). Clinical examination was normal.
Laboratory findings showed hypokalemia and secondary hyperaldosteronism. Abdominal ultrasound and CT-scan revealed an about 2.5 cm measuring tumor of the left kidney.
Under antihypertensive treatment, a normal blood pressure profile could be achieved. With the diagnosis of a reninoma the patient was transferred to the urology department for tumor resection. In a 3-month follow-up the patient was normotensive without any medication.
Renin-secreting juxtaglomerular tumor of the kidney (reninoma) is a very rare but curable cause of severe hypertension. The syndrome of "primary hyperreninism" is characterized by severe hypertension, hypokalemia, secondary hyperaldosteronism and a renal mass in sonography.
一名20岁无症状男性因严重高血压（250/150 mmHg）入院。临床检查正常。
实验室检查结果显示低钾血症和继发性醛固酮增多症。腹部超声和CT扫描显示左肾有一个大小约2.5 cm的肿瘤。
在抗高血压治疗下，血压可恢复正常。诊断为肾素瘤后，患者被转至泌尿外科进行肿瘤切除。在3个月的随访中，患者血压正常，无需任何药物治疗。
肾素分泌性肾小球旁细胞瘤（肾素瘤）是导致严重高血压的一种非常罕见但可治愈的病因。“原发性高肾素血症”综合征的特征为严重高血压、低钾血症、继发性醛固酮增多症以及超声检查发现肾脏肿块。
