Gottardo Fedra, Cesari Maurizio, Morra Aldo, Gardiman Marina, Fassina Ambrogio, Dal Bianco Massimo
Centre for Reproductive Medicine and Andrology, University of Münster, Germany. Fedra.Gottardo @ ukmuenster.de
Urol Int. 2010;85(1):121-4. doi: 10.1159/000314339. Epub 2010 May 5.
This report presents a case of a 16-year-old hypertensive boy who presented to our clinic. Laboratory findings showed severe hypokalemia and markedly increased plasma renin activity. Abdominal ultrasonography and contrast-enhanced computed tomography of the abdomen revealed a well-circumscribed, solid, hypoenhancing cortical lesion (2 cm) in the lower pole of the left kidney. The patient underwent nephron-sparing surgery. Histopathologic examination gave a diagnosis of juxtaglomerular cell tumor. Reninoma is an uncommon cause of hypertension in a young adult and should be included in the differential diagnosis as a potential life-threatening and curable condition. The conservative surgical management is the gold standard for small, circumscribed lesions.
本报告介绍了一名16岁高血压男孩到我们诊所就诊的病例。实验室检查结果显示严重低钾血症和血浆肾素活性显著升高。腹部超声和腹部增强计算机断层扫描显示左肾下极有一个边界清晰的实性低密度强化皮质病变（2厘米）。患者接受了保留肾单位手术。组织病理学检查诊断为球旁细胞瘤。肾素瘤是年轻成年人高血压的罕见病因，作为一种潜在的危及生命但可治愈的疾病，应列入鉴别诊断。保守手术治疗是小的、边界清晰病变的金标准。
