卵巢癌中子宫内膜异位症的患病率。

Prevalence of endometriosis in ovarian cancer.

作者信息

Yoshikawa H, Jimbo H, Okada S, Matsumoto K, Onda T, Yasugi T, Taketani Y

机构信息

Department of Obstetrics and Gynecology, University of Tokyo, Tokyo, Japan.

出版信息

Gynecol Obstet Invest. 2000;50 Suppl 1:11-7. doi: 10.1159/000052873.

DOI:10.1159/000052873

PMID:11093056

Abstract

Endometriosis may be the precursor of clear cell or endometrioid ovarian cancer. In this review, we focus on the prevalence of endometriosis in ovarian cancer and related clinical and epidemiological issues. According to 15 published reports, the rank order of the prevalence of endometriosis in each histologic type was clear cell (39.2%) > endometrioid (21.2%) > serous (3.3%) > mucinous type (3.0%). The high prevalence of endometriosis in clear cell and endometrioid types is a consistent finding in Japan and western countries. However, the incidence of the clear cell type is much higher (15-20% vs. 7-8%), and that of the endometrioid type is lower (7-16% vs. 18-26%), in Japan compared with western countries. This review is also concerned with the relationship between the presence of ovarian endometriosis and clinical features such as age, parity, menopausal status, clinical stage, and survival in ovarian cancer patients.

摘要

子宫内膜异位症可能是透明细胞癌或子宫内膜样卵巢癌的前驱病变。在本综述中，我们重点关注子宫内膜异位症在卵巢癌中的患病率以及相关临床和流行病学问题。根据15篇已发表的报告，子宫内膜异位症在各组织学类型中的患病率排序为：透明细胞型（39.2%）＞子宫内膜样型（21.2%）＞浆液性（3.3%）＞黏液性（3.0%）。在日本和西方国家，透明细胞型和子宫内膜样型中子宫内膜异位症的高患病率是一致的发现。然而，与西方国家相比，日本透明细胞型的发病率要高得多（15 - 20% 对 7 - 8%），而子宫内膜样型的发病率则较低（7 - 16% 对 18 - 26%）。本综述还关注卵巢子宫内膜异位症的存在与卵巢癌患者的年龄、产次、绝经状态、临床分期及生存等临床特征之间的关系。