Vargas-Hernández Víctor Manuel
Dirección de Investigación, Hospital Juárez de México, Secretaría de Salud, DF, Mexico.
Cir Cir. 2013 Mar-Apr;81(2):163-8.
A history of endometriosis is a risk factor for some subtypes of epithelial ovarian cancer. Endometriosis is associated with increased risk of ovarian clear cell, serous low-grade endometrioid cancer, but it is unclear what the role of endometriosis is in the development of other histopathological subtypes of ovarian cancer, such as high-grade serous borderline tumors subtypes or borderline serous and mucinous cancers. An understanding of the mechanisms leading to malignant transformation of endometriosis will be needed to identify subgroups of women at increased risk of ovarian cancer. This is important because of their high prevalence and cause of infertility in Mexico and the world. All factors must be considered during the decision-making process for the treatment of endometriosis, including the rare malignant transformation.
子宫内膜异位症病史是某些上皮性卵巢癌亚型的危险因素。子宫内膜异位症与卵巢透明细胞癌、浆液性低级别子宫内膜样癌风险增加相关，但目前尚不清楚子宫内膜异位症在其他组织病理学亚型的卵巢癌（如高级别浆液性交界性肿瘤亚型或交界性浆液性和黏液性癌）发生发展中所起的作用。需要了解导致子宫内膜异位症恶变的机制，以识别卵巢癌风险增加的女性亚组。鉴于其在墨西哥乃至全球的高发病率以及导致不孕的原因，这一点很重要。在子宫内膜异位症的治疗决策过程中，必须考虑所有因素，包括罕见的恶变情况。
