[囊性纤维化患儿静息能量消耗的评估]

[Evaluation of resting energy expenditure in children with cystic fibrosis].

作者信息

Ksiazyk J

机构信息

Klinika Pediatrii, Instytut Matki i Dziecka, Kasprzaka 17a, 01-211, Warszawa, Poland.

出版信息

Med Wieku Rozwoj. 2000 Jul-Sep;4(3):225-31.

PMID:11093340

Abstract

UNLABELLED

The aim of the investigation was to assess resting energy expenditure (REE) and substrate utilisation rate in children with cystic fibrosis. Body mass coefficient was below normal limits in 2 out of 14 controls and in 9 out of 10 patients with cystic fibrosis (p < 0.001). REE and basal energy expenditure (BEE) in the patient group were respectively 52.2 +/- 8.7 kcal/kg and 45.7 +/- 8.9 kcal/kg (p < 0.006). REE/BEE ratios in relation to total body mass were 115.34 +/- 12.27% and 93.54 +/- 4.47% (p < 0.001). REE / BEE ratio in relation to lean body mass 102.95 +/- 11.5% and 92.94 +/- 5.74% (p < 0.007). Substrate oxidation rate in the patient group and control group (g/kg) were: glycogen: 4.13 +/- 2.32 and 1.91 +/- 0.81 (p < 0.004); fat: 2.76 +/- 1.39 and 1.51 +/- 0.59 (p < 0.006); protein: 1.98 +/- 0.45 and 1.32 +/- 0.40 (p < 0.001).

IN CONCLUSION

In children with cystic fibrosis, malnutrition was found with increase REE which resulted from higher substrate utilisation rate as compared with the control group.

摘要

未标注

本研究的目的是评估囊性纤维化患儿的静息能量消耗（REE）和底物利用率。14名对照组儿童中有2名以及10名囊性纤维化患者中有9名的体重系数低于正常范围（p < 0.001）。患者组的REE和基础能量消耗（BEE）分别为52.2±8.7千卡/千克和45.7±8.9千卡/千克（p < 0.006）。相对于总体重的REE/BEE比值分别为115.34±12.27%和93.54±4.47%（p < 0.001）。相对于去脂体重的REE/BEE比值分别为102.95±11.5%和92.94±5.74%（p < 0.007）。患者组和对照组的底物氧化率（克/千克）分别为：糖原：4.13±2.32和1.91±0.81（p < 0.004）；脂肪：2.76±1.39和1.51±0.59（p < 0.006）；蛋白质：1.98±0.45和1.32±0.40（p < 0.001）。