Suppr超能文献

布比卡因和芬太尼在泌尿外科手术脊髓麻醉中的应用。

The use of bupivacaine and fentanyl for spinal anesthesia for urologic surgery.

作者信息

Kuusniemi K S, Pihlajamäki K K, Pitkänen M T, Helenius H Y, Kirvelä O A

机构信息

Department of Anaesthesiology and Biostatistics, University of Turku, Finland.

出版信息

Anesth Analg. 2000 Dec;91(6):1452-6. doi: 10.1097/00000539-200012000-00029.

Abstract

We evaluated the effect of 25 microg of fentanyl added to bupivacaine on sensory and motor block. By using a double-blinded study design, 80 men undergoing urologic surgery were randomized into the following four groups: Group I, bupivacaine 10 mg; Group II, bupivacaine 10 mg + fentanyl 25 microg; Group III, bupivacaine 7.5 mg + fentanyl 25 microg; Group IV, bupivacaine 5 mg + fentanyl 25 microg. The final volume of intrathecal injectate was adjusted to 2. 5 mL with sterile distilled water. Spinal anesthesia was administered with the 27-gauge Whitacre needle at the L2-3 interspace with the patient in the sitting position. Neural block was assessed by using pinprick and a modified Bromage scale. The degree of motor block was more profound in Group II compared with Group I at the end of operation. In Group IV, there was no motor block at the end of operation in any of the patients. The median level of the upper limit of the sensory block was higher than T(7) in all groups before the start of surgery. The addition of 25 microg of fentanyl to 5 mg of bupivacaine resulted in short-acting motor block. When 25 microg of fentanyl was added to 10 mg of bupivacaine, it increased the intensity and duration of motor block. Only 5 (6. 3%) of the patients needed supplemental analgesia during the operation. ¿abs¿

摘要

我们评估了在布比卡因中添加25微克芬太尼对感觉和运动阻滞的影响。采用双盲研究设计,将80例接受泌尿外科手术的男性随机分为以下四组:第一组,布比卡因10毫克;第二组,布比卡因10毫克 + 芬太尼25微克;第三组,布比卡因7.5毫克 + 芬太尼25微克;第四组,布比卡因5毫克 + 芬太尼25微克。鞘内注射剂的最终体积用无菌蒸馏水调整至2.5毫升。患者取坐位,使用27号Whitacre针在L2 - 3间隙进行脊髓麻醉。通过针刺和改良的 Bromage 量表评估神经阻滞。与第一组相比,手术结束时第二组的运动阻滞程度更深。在第四组中,所有患者在手术结束时均无运动阻滞。手术开始前,所有组感觉阻滞上限的中位水平均高于T(7)。在5毫克布比卡因中添加25微克芬太尼导致短效运动阻滞。当在10毫克布比卡因中添加25微克芬太尼时,它增加了运动阻滞的强度和持续时间。只有5例(6.3%)患者在手术期间需要补充镇痛。¿abs¿

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验