Suppr超能文献

0.5% 重比重布比卡因蛛网膜下腔麻醉诱导后体位改变对经皮肾镜取石术患者镇痛时间及阿片类药物需求的影响

Effect of Position Change After Induction of Spinal Anesthesia with Hyperbaric 0.5% Bupivacaine on Duration of Analgesia and Opioid Demand in Percutaneous Nephrolithotomy Candidates.

作者信息

Jaffari Alireza, Aghamohammadi Homayoun, Forouzmehr Masoud

机构信息

Anesthesiology Research Center, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Department of Anesthesiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Anesth Pain Med. 2025 Jan 21;15(1):e153617. doi: 10.5812/aapm-153617. eCollection 2025 Feb 28.

Abstract

BACKGROUND

Post-induction positioning influences the onset speed of the sensory block by affecting anesthetic distribution. Techniques such as using opioids and extending recovery stays aim to enhance this process.

OBJECTIVES

This study aimed to evaluate the impact of transitioning patients from a sitting to a lateral position immediately after the induction of 0.5% hyperbaric bupivacaine spinal anesthesia on postoperative pain and opioid consumption.

METHODS

In this prospective, randomized clinical trial, patients scheduled for percutaneous nephrolithotomy (PCNL) under spinal anesthesia at Shahid Labafinejad Hospital in 2023 were divided into intervention (lateral position) and control (supine position) groups. Blood pressure, mean arterial pressure (MAP), and heart rate were recorded upon entering recovery, then every 10 minutes up to 60 minutes, and every 15 minutes up to 120 minutes post-operation. Pain levels were assessed using the Visual Analogue Scale (VAS) at specified intervals. Patient satisfaction with analgesia quality was also evaluated.

RESULTS

The study included 35 patients in the lateral group and 34 in the supine group. Pain levels significantly differed between the groups over time (P = 0.0001). The lateral group had a longer analgesia duration (28.8 ± 10.0 minutes vs. 22.9 ± 2.9 minutes, P = 0.105) and lower total narcotic consumption (21.7 ± 5.8 mg vs. 30.4 ± 10.2 mg, P = 0.012). Mean arterial pressure changes showed no significant difference (P = 0.061). Patient satisfaction was significantly higher in the lateral group (P = 0.0001).

CONCLUSIONS

Transitioning from the sitting to lateral position post-induction with hyperbaric bupivacaine enhances hemodynamic stability, improves drug distribution in the cerebrospinal fluid (CSF), and enhances sensory block quality. This approach increases postoperative analgesia duration, reduces opioid use and related complications, and decreases the duration of surgery.

摘要

背景

诱导后体位通过影响麻醉药分布来影响感觉阻滞的起效速度。使用阿片类药物和延长恢复时间等技术旨在增强这一过程。

目的

本研究旨在评估在0.5%高压布比卡因蛛网膜下腔麻醉诱导后立即将患者从坐位转为侧卧位对术后疼痛和阿片类药物消耗的影响。

方法

在这项前瞻性随机临床试验中,2023年在沙希德拉巴菲内贾德医院计划接受蛛网膜下腔麻醉下行经皮肾镜取石术(PCNL)的患者被分为干预组(侧卧位)和对照组(仰卧位)。进入恢复室时记录血压、平均动脉压(MAP)和心率,然后在术后60分钟内每10分钟记录一次,在术后120分钟内每15分钟记录一次。使用视觉模拟量表(VAS)在特定时间间隔评估疼痛程度。还评估了患者对镇痛质量的满意度。

结果

研究包括侧卧位组35例患者和仰卧位组34例患者。两组之间的疼痛程度随时间有显著差异(P = 0.0001)。侧卧位组的镇痛持续时间更长(28.8±10.0分钟对22.9±2.9分钟,P = 0.105),总麻醉药物消耗量更低(21.7±5.8毫克对30.4±10.2毫克,P = 0.012)。平均动脉压变化无显著差异(P = 0.061)。侧卧位组患者的满意度显著更高(P = 0.0001)。

结论

诱导后使用高压布比卡因从坐位转为侧卧位可增强血流动力学稳定性,改善脑脊液(CSF)中的药物分布,并提高感觉阻滞质量。这种方法可延长术后镇痛持续时间,减少阿片类药物的使用及相关并发症,并缩短手术时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67c0/12125665/46b24908929e/aapm-15-1-153617-i001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验