淋巴细胞重排、编辑和修正其抗原受体，使其既有用又安全。

Lymphocytes rearrange, edit and revise their antigen receptors to be useful yet safe.

作者信息

Fink P J, McMahan C J

机构信息

University of Washington, Dept of Immunology, Seattle, WA 98195, USA.

出版信息

Immunol Today. 2000 Nov;21(11):561-6. doi: 10.1016/s0167-5699(00)01734-5.

DOI:10.1016/s0167-5699(00)01734-5

PMID:11094260

Abstract

Pamela Fink and Catherine McMahan discuss how B and T cells test for useful antigen receptors and weed out potentially harmful ones, with special attention paid to T-cell receptor revision, a newly described mechanism by which mature T cells can maintain self tolerance.

摘要

帕梅拉·芬克和凯瑟琳·麦克马汉讨论了B细胞和T细胞如何检测有用的抗原受体并清除潜在有害的受体，特别关注了T细胞受体修正，这是一种新描述的机制，通过该机制成熟T细胞可以维持自身耐受性。