Suh J H, Shin C S
Department of Biotechnology, College of Engineering and the Bioproducts Research Center, Yonsei University, Sudaemun-ku, 120-749, Seoul, South Korea.
FEMS Microbiol Lett. 2000 Dec 1;193(1):143-7. doi: 10.1111/j.1574-6968.2000.tb09416.x.
Changes in cell life cycle and intracellular structure of Monascus sp. J101 by coculture with Saccharomyces cerevisiae were investigated. Cocultured Monascus cells showed accelerated cell growth and reproduction. Production of asexual and sexual spores was used as an efficient method of cell proliferation. Formation of meiotic (sexual) spores was more frequently observed in the cocultured Monascus cells. The interior structure of a cocultured cell was characterized by increased numbers and sizes of vacuoles. The vacuoles probably serve as repositories for pigment storage. Pigments produced by the cocultured Monascus cells were more hydrophobic than pigments produced by control cells with no coculture.
研究了红曲霉菌株J101与酿酒酵母共培养后细胞生命周期和细胞内结构的变化。共培养的红曲霉菌细胞显示出细胞生长和繁殖加速。无性和有性孢子的产生被用作细胞增殖的有效方法。在共培养的红曲霉菌细胞中更频繁地观察到减数分裂（有性）孢子的形成。共培养细胞的内部结构特征是液泡数量和大小增加。液泡可能作为色素储存的场所。共培养的红曲霉菌细胞产生的色素比未进行共培养的对照细胞产生的色素更疏水。
