Njeh C F, Genant H K
Department of Radiology, University of California, San Francisco, California 94143, USA.
Arthritis Res. 2000;2(6):446-50. doi: 10.1186/ar126. Epub 2000 Aug 3.
Osteoporosis is associated with low bone mass and microarchitectural deterioration of bone tissue with clinical manifestation of low trauma fractures. Rheumatoid arthritis (RA) is a risk factor due to generalized and articular bone loss. This minireview presents past and current bone mass measurement techniques in RA. These techniques include: plain radiographs, absorptiometry, quantitative computed tomography (QCT) and ultrasound. The most widely used technique is dual x-ray absorptiometry (DXA). RA patients have lower bone mass as compared with normals and substantial bone loss may occur early after the onset of disease. Measurement of bone mineral density (BMD) at the hand using either DXA or ultrasound maybe a useful tool in the management of RA patients.
骨质疏松症与骨量低及骨组织微结构退化有关，临床表现为低创伤性骨折。类风湿性关节炎（RA）是导致全身性和关节性骨质流失的一个风险因素。这篇微型综述介绍了过去和当前用于测量RA患者骨量的技术。这些技术包括：普通X线片、吸收测定法、定量计算机断层扫描（QCT）和超声检查。使用最广泛的技术是双能X线吸收测定法（DXA）。与正常人相比，RA患者的骨量较低，且在疾病发作后早期可能会出现大量骨质流失。使用DXA或超声检查测量手部骨矿物质密度（BMD）可能是管理RA患者的一种有用工具。
