Kellum J A, Bellomo R
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Crit Care. 2000;4(2):69-71. doi: 10.1186/cc659. Epub 2000 Feb 16.
Hemofiltration as an adjunct to therapy for sepsis is now 10 years old. Despite early successes and significant theoretical advantages, the treatment remains experimental. Although feasibility has been established, efficacy has proved to be much more difficult. Clinical as well as technical difficulties remain important considerations to future studies. These issues are discussed and the brief history of hemofiltration in sepsis is reviewed.
血液滤过作为脓毒症治疗的辅助手段至今已有10年历史。尽管早期取得了成功且具有显著的理论优势,但该治疗仍处于试验阶段。虽然已证实其可行性,但疗效却困难得多。临床和技术难题仍是未来研究的重要考量因素。本文将对这些问题进行讨论,并回顾脓毒症血液滤过的简短历史。