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[持续高容量血液滤过在脓毒症和多器官功能障碍患者中的应用]

[Use of continuous high-volume hemofiltration in patients with sepsis and multiple organ dysfunction].

作者信息

Biriukova L S, Purlo N V, Denisova E N, Mondoev L G, Levina A A, Galstian G M

出版信息

Anesteziol Reanimatol. 2005 Mar-Apr(2):69-71.

PMID:15938103
Abstract

The paper gives the authors' experience in performing continuous high-volume hemofiltration in 38 patients with sepsis and multiple organ failure. The kinetics of proinflammatory cytokines and a number of plasma enzymes as markers of substances having a relatively high molecular mass was studied. The advantages of a procedure using an artificial kidney apparatus equipped with an on-line substituting fluid preparation system are described. The possibilities of correcting the parameters of homeostasis are the principles of maintenance of a hemostatic system in this group of patients during the procedure are presented. The drawbacks of this technique are also described.

摘要

本文介绍了作者对38例脓毒症和多器官功能衰竭患者进行持续大容量血液滤过的经验。研究了促炎细胞因子和多种血浆酶作为相对高分子质量物质标志物的动力学。描述了使用配备在线置换液制备系统的人工肾装置进行该操作的优点。提出了在该组患者手术过程中纠正内环境稳态参数及维持止血系统的原则。还描述了该技术的缺点。

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