Lacroix I, Damase-Michel C, Lapeyre-Mestre M, Montastruc J L
Lancet. 2000 Nov 18;356(9243):1735-6. doi: 10.1016/s0140-6736(00)03209-8.
A survey of the records of the French Health Insurance Service of drug prescriptions during pregnancy in 1000 women living in Haute-Garonne, southwest France, showed that 99% of the women received a prescription for at least one drug during pregnancy with a mean of 13.6 medications per woman. 1.6% of women received one or more prescriptions of drugs from the US Food and Drug Administration X category (fetal risk outweighs benefits). 59% of women had a prescription of drugs from the D category (fetal risk but benefits may be acceptable) and 79% of women were exposed to drugs for which information about safety in pregnancy was not available from animal or human studies.
对居住在法国西南部上加龙省的1000名孕妇的法国医疗保险服务机构的药物处方记录进行的一项调查显示,99%的女性在孕期至少收到了一种药物的处方,平均每位女性有13.6种药物。1.6%的女性收到了美国食品药品监督管理局X类(胎儿风险大于益处)的一种或多种药物处方。59%的女性有D类(有胎儿风险但益处可能可接受)药物的处方,79%的女性接触到了在动物或人体研究中没有关于孕期安全性信息的药物。